参考答案和解析
正确答案:指能刺激机体免疫系统中的免疫细胞发生免疫应答,产生免疫产物(效应细胞或抗体),并能与免疫产物发生特异性反应的物质。
更多“抗原(antigen)”相关问题
  • 第1题:

    人类ABO血型抗原包括

    A、A抗原和O抗原

    B、B抗原和O抗原

    C、H抗原

    D、A抗原、B抗原和O抗原

    E、A抗原和B抗原


    参考答案:E

  • 第2题:

    副溶血牲弧菌具有的抗原是

    A.O抗原、H抗原、K抗原

    B.D抗原、H抗原、K抗原

    C.F抗原、H抗原、K抗原

    D.O抗原、B抗原、A抗原

    E.O抗原、A抗原、C抗原


    正确答案:A

  • 第3题:

    共用题干
    第一篇

    Immune Functions

    The immune system is equal in complexity to the combined intricacies of the brain and nervous system.
    The success of the immune system in defending the body relies on a dynamic regulatory communication net-
    work consisting of millions and millions of cells.Organized into sets and subsets,these cells pass information
    back and forth like clouds of bees flying around a hive(蜂巢).The result is a sensitive system of checks and
    balances that produces an immune response that is prompt,appropriate,effective,and self-limiting.
    At the heart of the immune system is the ability to distinguish between self and nonself. When immune
    defenders encounter cells or organisms carrying foreign or nonself molecules,the immune troops move quickly
    to eliminate the intruders(人侵者).Virtually every body cell carries distinctive molecules that identify it as
    self. The body's immune defenses do not normally attack tissues that carry a self-marker. Rather,immune
    cells and other body cells coexist peaceably in a state known as self-tolerance.When a normally functioning
    immune system attacks a nonself molecule,the system has the ability to"remember"the specifics of the
    foreign body.Upon subsequent encounters with the same species of molecules,the immune system reacts
    accordingly. With the possible exception of antibodies(抗体)passed during lactation(授乳期), this so
    called immune system memory is not inherited.Despite the occurrence of a virus in your family,your immune
    system must"learn"from experience with the many millions of distinctive nonseif molecules in the sea of
    microbes(微生物)in which we live. Learning entails producing the appropriate molecules and cells to match
    up with and counteract each nonseif invader.
    Any substance capable of triggering an immune response is called an antigen(抗原).Antigens are not
    to be confused with illergens(过敏原),which are most often harmless substances that provoke the immune
    system to set off the inappropriate and harmful response known as allergy.An antigen can be a virus,a bacte-
    rium,or even a portion or product of one of these organisms.Tissues or cells from another individual also act
    as antigens,because the immune system recognizes transplanted tissues as foreign,it rejects them.The body
    will even reject nourishing proteins unless they are first broken down by the digestive system into their
    primary,nonantigenic building blocks.An antigen announces its foreignness by means of intricate and charac-
    teristic shapes called epitopes(抗原表位), which protrude(突出)from its surface. Most antigens , even the
    simplest microbes,carry several different kinds of epitopes on their surface;some may even carry several
    hundreds.Some epitopes will be more effective than others at stimulating an immune response.Only in abnormal
    situations does the immune system wrongly identify self as nonself and execute a misdirected immune attack.

    Which of the following best expresses the main idea of this passage?
    A:An antigen is any substance that triggers an immune response.
    B:One of the immune system's primary functions is the allergic response.
    C:The human body is an appropriate habitat for microbes.
    D:The basic function of the immune system is to distinguish between self and nonseif.

    答案:D
    解析:
    由第一段第三句中的“like clouds of bees flying around a hive”可知选B。
    由文章第二段第五句可知答案为A。
    由文章最后一段中的“An antigen announces its foreignness by …characteristic shapes …" 可知选C。
    由文章最后一段第一句可知,能引起免疫反应的物质叫抗原,即抗原能引起免疫反应, 故选B
    由文章第二段第一句“At the heart of the immune system...”可知选D。 heart相当 于basic。

  • 第4题:

    细胞毒T淋巴细胞抗原-4(cytotoxic T lymphocyte antigen-4,CTLA-4)


    正确答案: 细胞毒T淋巴细胞抗原-4(cytotoxic T lymphocyte antigen-4,CTLA-4)又称为CD152,为同源二聚体,表达于活化的T细胞上,其胞浆区可与磷酸酶(SHP-1、SHIP)结合,对T细胞具有负调节作用。它和CD28分子均能与CD80/CD86结合,共同调节免疫应答。

  • 第5题:

    HLAⅡ类抗原(HLA class Ⅱ antigen)


    正确答案:是由α、β两条多肽链借非共价键连接组成的二聚体糖蛋白分子,两条链均有多态性,分子量分别为3400ODa(α)和2900ODa(β)。HLAⅡ类抗原是由第6号染色体HLAⅡ类基因编码的产物,HLAⅡ类抗原分子可分为四个区,即抗原肽结合区、免疫球蛋白样区(Ig样区)、跨膜区、胞内区。主要分布于B细胞、巨噬细胞和其他抗原提呈细胞表面,以及胸腺上皮细胞和活化T细胞表面;在血管内皮细胞和精子细胞上也可少量表达。

  • 第6题:

    抗原呈递细胞(antigen presenting cell,APC)


    正确答案:指能够捕获、加工处理抗原,并将抗原呈递给抗原特异性淋巴细胞的一类免疫细胞。主要包括单核吞噬细胞、树突状细胞和B细胞等。

  • 第7题:

    Fab(Fragment antigen binding)


    正确答案:即抗原结合片段,每个Fab段由一条完整的轻链和重链的VH和CH1功能区构成,可以与抗原表位发生特异性结合。

  • 第8题:

    抗原提呈细胞(antigen presenting cell,APC)


    正确答案: 是指具有摄取、加工、处理抗原,并能将抗原信息提呈给淋巴细胞的一类细胞。

  • 第9题:

    胸腺非依赖性抗原(thymus independent antigen,TI-Ag)


    正确答案: 是一类不需要Th细胞辅助即可诱导抗体产生的抗原。该抗原由B细胞丝裂原及多个重复的B表位组成,可使不成熟及成熟的B细胞应答,只产生体液免疫应答,不产生细胞免疫应答。

  • 第10题:

    T细胞抗原受体复合体(T—cell antigen receptor complex,TCRC)


    正确答案: 由T细胞膜表面特异性抗原受体TCR与CD3分子组成,其中TCR是特异性抗原受体,CD3是向胞内传递激活信号的信号传递单位。

  • 第11题:

    单选题
    沙门菌抗原非常复杂,下列哪组属于主要的具有分类学意义的抗原?(  )
    A

    O抗原、H抗原、M抗原

    B

    H抗原、K抗原、Vi抗原

    C

    K抗原、M抗原、5抗原

    D

    O抗原、H抗原、Vi抗原

    E

    Vi抗原、5抗原、M抗原


    正确答案: E
    解析:
    抗原结构主要由O抗原和H抗原组成,部分菌株有类似大肠杆菌K抗原的表面抗原,与细菌的毒力有关,故称Vi抗原。已证实沙门菌属的表面抗原有Vi、M和5抗原三种。

  • 第12题:

    名词解释题
    Tumor specific antigen

    正确答案: 即肿瘤特异性抗原,指仅表达于肿瘤组织,而不存在于正常组织的肿瘤抗原,化学或物理因素诱生的肿瘤抗原、自发肿瘤抗原和病毒诱导的肿瘤抗原等多属此类。
    解析: 暂无解析

  • 第13题:

    下列关于前列腺特异性抗原(prostate-specific antigen,PSA)的说法,不正确的是()

    A.血清PSA为组织特异性而非疾病特异性

    B.PSA升高对前列腺癌,特别是高分化癌有较高的诊断价值

    C.PSA检查应在前列腺的直肠指诊前1周

    D.PSA检测时应无急性前列腺炎、尿潴留

    E.PSA检查应在膀胱镜检查、导尿等操作后48小时


    答案:C

  • 第14题:

    链球菌的抗原主要有

    A、糖蛋白抗原,脂多糖抗原,核蛋白抗原

    B、蛋白抗原,脂多糖抗原,核蛋白抗原

    C、膜蛋白抗原,多糖抗原,核蛋白抗原

    D、膜蛋白抗原,脂多糖抗原,核蛋白抗原

    E、蛋白抗原,多糖抗原,核蛋白抗原


    参考答案:E

  • 第15题:

    共用题干
    第一篇

    Immune Functions

    The immune system is equal in complexity to the combined intricacies of the brain and nervous system.
    The success of the immune system in defending the body relies on a dynamic regulatory communication net-
    work consisting of millions and millions of cells.Organized into sets and subsets,these cells pass information
    back and forth like clouds of bees flying around a hive(蜂巢).The result is a sensitive system of checks and
    balances that produces an immune response that is prompt,appropriate,effective,and self-limiting.
    At the heart of the immune system is the ability to distinguish between self and nonself. When immune
    defenders encounter cells or organisms carrying foreign or nonself molecules,the immune troops move quickly
    to eliminate the intruders(人侵者).Virtually every body cell carries distinctive molecules that identify it as
    self. The body's immune defenses do not normally attack tissues that carry a self-marker. Rather,immune
    cells and other body cells coexist peaceably in a state known as self-tolerance.When a normally functioning
    immune system attacks a nonself molecule,the system has the ability to"remember"the specifics of the
    foreign body.Upon subsequent encounters with the same species of molecules,the immune system reacts
    accordingly. With the possible exception of antibodies(抗体)passed during lactation(授乳期), this so
    called immune system memory is not inherited.Despite the occurrence of a virus in your family,your immune
    system must"learn"from experience with the many millions of distinctive nonseif molecules in the sea of
    microbes(微生物)in which we live. Learning entails producing the appropriate molecules and cells to match
    up with and counteract each nonseif invader.
    Any substance capable of triggering an immune response is called an antigen(抗原).Antigens are not
    to be confused with illergens(过敏原),which are most often harmless substances that provoke the immune
    system to set off the inappropriate and harmful response known as allergy.An antigen can be a virus,a bacte-
    rium,or even a portion or product of one of these organisms.Tissues or cells from another individual also act
    as antigens,because the immune system recognizes transplanted tissues as foreign,it rejects them.The body
    will even reject nourishing proteins unless they are first broken down by the digestive system into their
    primary,nonantigenic building blocks.An antigen announces its foreignness by means of intricate and charac-
    teristic shapes called epitopes(抗原表位), which protrude(突出)from its surface. Most antigens , even the
    simplest microbes,carry several different kinds of epitopes on their surface;some may even carry several
    hundreds.Some epitopes will be more effective than others at stimulating an immune response.Only in abnormal
    situations does the immune system wrongly identify self as nonself and execute a misdirected immune attack.

    How do the immune cells recognize an antigen as"foreign"or"nonself"?
    A:Through an allergic response.
    B:Through blood type.
    C:Through characteristic shapes on the antigen surface.
    D:Through fine hairs protruding from the antigen surface.

    答案:C
    解析:
    由第一段第三句中的“like clouds of bees flying around a hive”可知选B。
    由文章第二段第五句可知答案为A。
    由文章最后一段中的“An antigen announces its foreignness by …characteristic shapes …" 可知选C。
    由文章最后一段第一句可知,能引起免疫反应的物质叫抗原,即抗原能引起免疫反应, 故选B
    由文章第二段第一句“At the heart of the immune system...”可知选D。 heart相当 于basic。

  • 第16题:

    抗原(antigen,Ag)


    正确答案: 能诱导机体产生体液抗体和细胞免疫应答,并能与抗体和致敏淋巴细胞在体内外发生特异结合反应的物质。

  • 第17题:

    抗原(antigen)


    正确答案:是指能与TCR/BCR或抗体结合,具有启动免疫应答潜能的物质

  • 第18题:

    胸腺依赖性抗原(thymus dependent antigen,TD-Ag)


    正确答案:是一类必须依赖Th细胞辅助才能诱导机体产生抗体的抗原。该抗原由T表位和B表位组成,绝大多数蛋白质类抗原为TD-Ag,可刺激机体产生体液免疫应答和细胞免疫应答。

  • 第19题:

    HLA I 类抗原(HLA class Ⅰ antigen)


    正确答案:是由轻、重两条多肽链借非共价键连接组成的异二聚体分子。重链(即α链)为多态性糖蛋白(分子量4400ODa),是由人第6号染色体HLAI类基因编码的产物;轻链为非多态性β微球蛋白(β2m,分子量12000Da),是由人第15号染色体相应基因编码的产物。HLAI类抗原分子可分为四个区,即抗原肽结合区、免疫球蛋白样区(Ig样区)、跨膜区、胞内区。HLAI抗原广泛分布于所有有核细胞、血小板和网织红细胞表面,而在神经细胞、成熟的滋养层细胞表面尚未检出;HLAI类抗原也存在于各种体液中。

  • 第20题:

    外源性抗原(exogenous antigen)


    正确答案: 即来源于细胞外的抗原,如被吞噬的细菌或细胞等。

  • 第21题:

    主要组织相容性抗原(major histocompatibility antigen)


    正确答案: 代表个体特异性的引起移植排斥反应的同种异型抗原称为组织相容性抗原,其中能引起强烈而迅速排斥反应的抗原系统称为主要组织相容性抗原。

  • 第22题:

    抗原提呈(antigen presenting)


    正确答案:主要指抗原提呈细胞(APC.将抗原肽通过MHC1类分子和/或MHCII类分子提呈给CD8+T细胞的过程。抗原提呈包括抗原的摄取(内源性抗原则在胞内合成)、处理、运输至细胞膜表面以及供T细胞TCR识别等过程。

  • 第23题:

    名词解释题
    细胞毒T淋巴细胞抗原-4(cytotoxic T lymphocyte antigen-4,CTLA-4)

    正确答案: 细胞毒T淋巴细胞抗原-4(cytotoxic T lymphocyte antigen-4,CTLA-4)又称为CD152,为同源二聚体,表达于活化的T细胞上,其胞浆区可与磷酸酶(SHP-1、SHIP)结合,对T细胞具有负调节作用。它和CD28分子均能与CD80/CD86结合,共同调节免疫应答。
    解析: 暂无解析

  • 第24题:

    名词解释题
    Fetal antigen

    正确答案: 胚胎抗原是在胚胎发育阶段由胚胎组织产生的正常成分,在胚胎后期减少,出生后逐渐消失,或仅存留极微量,当细胞癌变时,此类抗原可重新合成,水平大大提高。
    解析: 暂无解析